Overview
The main target of PharmacoScreen Panel is the genes associated
with prescribed drugs of the corresponding diseases.
to allow for client-specific selection.
- Standard
-
The PharmacoScreen Standard panel is designed to research organ transplant-related genes
through assessment of drug metabolism, transporters, and Parkinson's disease-related genes.
- Epilepsy
-
The PharmacoScreen Epilepsy panel is designed for genetic researches related to anti-epileptic
drugs. Our panel is also useful for assessing an individual's genetic characteristics to accurately
prescribe relevant drugs.
- Anti-tuberculosis
- The main target of the PharmacoScreen Anti-tuberculosis panel is the genes
associated with a drug-induced liver injury which is an important factor for drug
development as well as precise drug prescription
Features &
Benefits
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- Assess extensive target regions associated with pharmacogenomics
- Target over 120 genes associated with Pharmacokinetics
and Pharmacodynamics
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- Validated panel performance
- Collaborated with 4 major university hospitals with proven clinical usage
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- Flexible panel contents
- PharmacoScreen Standard, PharmacoScreen Epilepsy,
PharmacoScreen Antituberculosis
List Of Genes
The target genes of each PharmacoScreen Panel are listed in table below. If the panel does not contain their specific genes of interest, customers can add those genes into Celemics' pre-set panels through our additional service. Please contact us for more information.
PharmacoScreen Panel - Standard
| Pharmaco Screen Panel Standard |
ADH1B | ADH1C | ALDH1A1 | CES1 | CES2 | CYP1A1 | NR1I3 | CYP2A6 | CYP2B6 | CYP2C19 | CYP2C8 | CYP2C9 | CYP2D6 | CYP2E1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CYP2J2 | CYP2R1 | CYP3A4 | CYP3A5 | CYP4F2 | CYP7A1 | DPYD | EPHX1 | PON1 | GSTM1 | GSTP1 | GSTT1 | NAT1 | NAT2 | |
| SULT1A1 | TPMT | UGT1A1 | UGT1A4 | UGT1A9 | UGT1A10 | UGT2B15 | UGT2B7 | ABCA1 | ABCB1 | ABCB11 | ABCC2 | ABCC3 | ABCC4 | |
| ABCC7 | ABCG1 | ABCG2 | SLC10A1 | SLC15A1 | SLC15A2 | SLC19A1 | SLC22A1 | SLC22A2 | SLC22A3 | SLC22A4 | SLC22A5 | SLC22A6 | SLC22A8 | |
| SLC22A11 | SLC22A12 | SLCO1A2 | SLCO1B1 | SLCO1B3 | SLCO2B1 | ACE | ADRB2 | BRCA1 | COMT | DRD2 | F5 | HMGCR | MTHFR | |
| NQO1 | P2RY1 | P2RY12 | PTGIS | SCN5A | TYMS | VDR | VKORC1 | ADRB1 | ALOX5 | APOA1 | ARID5B | BDNF | CACNA1C | |
| CPS1 | CRHR1 | DBH | DRD1 | EGFR | ESR1 | FKBP5 | GLCCI1 | GRK4 | GRK5 | G6PD | HTR1A | HTR2A | KCNH2 | |
| LDLR | MAOA | NR3C2 | NTRK2 | PEAR1 | PTGS1 | PTGS2 | RYR1 | RYR2 | SCN1A | SCN2A | SLC47A1 | SLC47A2 | SLC6A3 | |
| SLC6A4 | TBXAS1 | ZNF423 | AHR | KCNJ11 | NR1I3 | NR1I2 | POR | SOD2 |
PharmacoScreen Panel - Epilepsy
| Pharmaco Screen Panel Epilepsy |
ANKK1 | CACNA1A | CACNA1B | CACNA1D | CACNA1E | CACNA1F | CACNA1G | CACNA1H | CACNA1I | CACNA1S | CACNA2D1 | CACNA2D2 | CACNA2D3 | CACNA2D4 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CACNB1 | CACNB2 | CACNB3 | CACNB4 | CACNG1 | CACNG2 | CACNG3 | CACNG4 | CACNG5 | CACNG6 | CACNG7 | CACNG8 | CDH13 | CLCN2 | |
| EFHC1 | GABRA1 | GABRA2 | GABRA3 | GABRA4 | GABRA5 | GABRA6 | GABRB1 | GABRB2 | GABRB3 | GABRD | GABRE | GABRG1 | GABRG2 | |
| GABRG3 | GABRP | GABRQ | GABRR1 | GABRR2 | GABRR3 | GRIA1 | GRIA2 | GRIA3 | GRIA4 | GRIK1 | GRIK2 | GRIK3 | GRIK4 | |
| GRIK5 | GRIN1 | GRIN2A | GRIN2B | GRIN2C | GRIN2D | GRIN3A | GRIN3B | HNF4A | HTR1B | KCNA2 | KCNB1 | KCNC1 | KCND3 | |
| KCNH1 | KCNJ10 | KCNQ2 | KCNQ3 | KCNT1 | KCNTD7 | LEPR | MAOA | MAOB | RBFOX1 | SCN1A | SCN2A | SCN3A | SCN8A | |
| STS | TPH1 | TPH2 | UGT1A10 | UGT1A6 | UGT1A7 | UGT1A9 |
PharmacoScreen Panel - Anti-tuberculosis
| Pharmaco Screen Panel Anti- Tuberculosis |
ABHD5 | ADA | ADORA2A | ALAS1 | ALPK2 | ANO10 | ASAH1 | BACH1 | BAX | BCL2 | BTLA | CARD8 | CASP1 | CASP3 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CASP8 | CASP9 | CAT | CCL2 | CD274 | CD276 | CD28 | CD40 | CD40LG | CD80 | CD86 | CPA6 | CTLA4 | CYBA | |
| DDX10 | DPP4 | ENTPD1 | FAHD2A | FAS | FASLG | FBXW8 | FOXP3 | GCLC | GCLM | GGT1 | GPX1 | GPX3 | GPX4 | |
| GSR | GSS | GSTA1 | GSTA2 | GSTA3 | GSTA4 | GSTA5 | GSTK1 | GSTM2 | GSTM3 | GSTM4 | GSTM5 | GSTO1 | GSTO2 | |
| GSTT2 | GSTZ1 | HAVCR2 | HIF1A | HMOX1 | HMOX2 | HSPA1L | ICOS | ICOSLG | IDO1 | IDO2 | IFNG | IFNGR1 | IFNGR2 | |
| IL10 | IL10RA | IL12A | IL12B | IL12RB1 | IL12RB2 | IL17A | IL17RA | IL18 | IL18R1 | IL18RAP | IL1A | IL1B | IL1R1 | |
| IL4 | IL4R | IL6 | IL6R | KCNE3 | KCNIP3 | KEAP1 | KSR2 | LAG3 | LGALS9 | MAFK | MIR4272 | MPO | NFE2L2 | |
| NLRP3 | NOS1 | NOS2 | NOS3 | NT5E | PDCD1 | PDCD1LG2 | PLXNA4 | POLD3 | PROM2 | PSD3 | SOD1 | SOD3 | SRXN1 | |
| STAT3 | TGFB1 | TGFBR1 | THSD7B | TN | FRSF4 | TNF | TNFAIP3 | TNFRSF14 | TNFRSF1A | TNFRSF1B | TNFRSF9 | TNFSF10 | TNFSF14 | |
| TNFSF4 | TNFSF9 | TRIM43 | TXNRD1 | USP44 | VTCN1 | ZNF804B |
Applications
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Drug metabolism