Celemics Analysis Service

Trust CAS with your Bioinformatics Analysis

Overview

Revolutionary Bioinformatics Solution for your Sequencing Data

Although NGS-based molecular diagnosis technologies have advanced rapidly, existing bioinformatics analysis platforms have not matched the speed of development.

Even as the discovery of various new biomarkers and their applications are becoming more prevalent by the day, there are very few solutions in the market that are able to readily react to client needs. As such, Celemics has developed the Celemics Analysis Service (CAS), a revolutionary bioinformatics solution aiming to provide client-specific services for the current convoluted and restrictive market using real-time client interaction, need-based customized analysis, and the expertise of our bioinformatics analysts.

Celemics Analysis Service
Features & Benefits

Fast and Accurate Bioinformatics Analysis

CAS allows easy accession of analysis results, even with no prior knowledge of bioinformatics analysis. We can offer suitable analysis methodology based on experimental purpose, conditions, and status. (Germline, somatic, FFPE, cfDNA, RNA, virus, bacteria, non-human, de novo sequencing, methylation sequencing, or more).

Through automated bioinformatics pipeline and bioinformatics experts from Celemics, we provide constant monitoring of all analysis processes and results and also can support real-time troubleshooting and solution provision during analysis process, even for non-standard data sets.

At Celemics, we follow well accepted GATK Best practice pipeline and are GDPR-compliant through usage of Europe-based server.

Accurate Clinical Interpretation: Strand Clinical Report

Drug Response

Sophisticated Client-Customized Data Analysis

The benefit and advantage of using CAS is that we are able to support optimized analysis proposals based on client’s research or clinical purposes.

We propose individualized result data re-processing and visualization based on client needs as well as an annotation option based on additional databases per client request possible (Prior usage confirmation required).

Celemics’ in-house Bioinformaticians also support analysis pipelines other than Celemics’ standard pipelines to be developed based on real-time communication with clients.

Tertiary Analysis - Client-specific Visualization: OncoRisk CNV Analysis

Tertiary Analysis - Client-specific Visualization Curation:

FLT3-ITD Analysis visualized by IGV View

FLT3-ITD Analysis:
visualized by IGV View

Gene Fusion Analysis from FFPE samples

Gene Fusion Analysis from FFPE samples

Client Ease of Use

Because we understand the challenges that comes with data analyses in NGS, CAS emphasizes ease of use Bioinformatics solutions.

We reduce initial cost and time for account set-up and user training; instead, we present individual client-based custom analysis possible using a simple data input interface, removing the need for complicated request processes. Team of Celemics’ bioinformatics experts provide real-time real-time troubleshooting and recommendations for your analysis results. Additionally, NGS experts and Celemics continuously monitor the process for issues such as index hopping and will provide alternative solutions.

All results and reports are guaranteed fast data transmission speed and short transmission intervals using servers within the European region.

Secondary Analysis : CAS Visualized Report

Celemics Analysis Service

Other Features

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Cost-effective Service

No base account set-up or user registration fee as expert Bioinformaticians are ready to help with your analysis

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Provision of Result with Different Analytic-tiers

highly competitive primary / secondary / tertiary analysis (clinical interpretation included) depending on your needs.

Variants annotated with functional significance and incorporated with AMP Clinical Practice Guidelines

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Interoperability with Celemics Target Enrichment Panels

Able to generate analysis results optimized for Celemics panels along with user-friendly Bioinformatics report as per request

Workflow
celemics analysis service workflow

01. Analysis Request

[Primary Analysis]
FASTQ to annotated VCF

[Secondary Analysis]
CNV, Large InDel, Fusion, TMB & MSI

[Tertiary Analysis]
Clinical Interpretation

[Provision of client]
Requested reports such as BAM/BAI, Annotated VCF, Performance Summary Statistics, Clinical Reports, etc.

Will require prior consultation and agreement.

[Variant Filtration]
Provision of process report for mutation detection using metrics such as VAF, depth, and strand conditions.

[Variant Clinical Significance]
Gathering relevant data types based on clinical information such as mutation type, protein functions, clinical database, etc.

After confirming the analysis request, a Celemics Bl expert will initiate and monitor the analysis

[Data upload]
On-site server or cloud server
[single click, automated upload]

05. Result Guidance

04. Request Interpretaion

03. BI Analysis

02. Data Transmission

Customer

CELEMICS

Customer

Workflow
celemics analysis service workflow

[Primary Analysis]
FASTQ to annotated VCF

[Secondary Analysis]
CNV, Large InDel, Fusion, TMB & MSI

[Tertiary Analysis]
Clinical Interpretation

[Data upload]
On-site server or cloud server
[single click, automated upload]

After confirming the analysis request, a Celemics Bl expert will initiate and monitor the analysis

[Variant Filtration]
Provision of process report for mutation detection using metrics such as VAF, depth, and strand conditions.

[Variant Clinical Significance]
Gathering relevant data types based on clinical information such as mutation type, protein functions, clinical database, etc.

[Provision of client]
Requested reports such as BAM/BAI, Annotated VCF, Performance Summary Statistics, Clinical Reports, etc.

Will require prior consultation and agreement.

01. Analysis Request

02. Data Transmission

03. BI Analysis

04. Request Interpretaion

05. Result Guidance

Workflow

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Resources

Technical Resources

[Product Sheet] Celemics Analysis Service(CAS) Introduction

[Catalogue] Celemics Products & Service Catalogue_All Products & Service